Row operations of the methylation sites

yame rowop provides a fast and convenient way to perform some frequently used row operations such as obtaining the mean and standard deviation statistics from yame rowop -o mean and yame rowop -o std.

The most common use of yame rowop might be taking the sum of binary data to merge the pseudobulks. For example, we have a single cell methylation .cg file, and we want to merge cluster #1 to obatin the cluster #1 pseudobulks, we can combine this with yame subset by

yame subset -l cluster_1_id.txt single_cell.cg | yame rowop - -o binasum > single_cell_pseudobulk1.cg 

yame rowop also allows

1. Binarization of the .cg file with the output of binary strings using yame rowop -o binstring
2. Co-methylation patterns of neighboring CGs using yame rowop -o cometh.

For more help with rowop, run yame rowop in the terminal or check out the rowop help page.